When in Munich in the 1970s, he started his own record label called Oasis Records, which several years later became a subdivision of Casablanca Records. He produced singles for Donna Summer during the late-1970s disco era, including "Love to Love You Baby", "I Feel Love", "Last Dance", "MacArthur Park", "Hot Stuff", "Bad Girls", "Dim All the Lights", "No More Tears (Enough Is Enough)", and "On the Radio", and is the founder of the former Musicland Studios in Munich, a recording studio used by many artists including Electric Light Orchestra, Led Zeppelin, Queen and Elton John.
Moroder also composed the soundtrack for the film Midnight Express, which won an Academy Award and a Golden Globe, and contained the international hit "Chase". He also produced a number of electronic disco songs for the Three Degrees, two albums for Sparks, and a handful of songs on Bonnie Tyler's album Bitterblue as well as her 1985 single "Here She Comes". In 1990, he composed "Un'estate italiana", the official theme song of the 1990 FIFA World Cup.
He has created a score of songs for many performers including David Bowie, Kylie Minogue, Irene Cara, Janet Jackson, Madleen Kane, Melissa Manchester, Blondie, Japan and France Joli. Moroder has stated that the work of which he is most proud is Berlin's "Take My Breath Away", which earned him two Golden Globes (for Best Original Score and Best Original Song) and the Academy Award for Best Original Song in 1986; he had earned the same awards in 1983 for "Flashdance... What a Feeling". In addition to the three Academy Awards and four Golden Globes, Moroder has also received four Grammy Awards, two People's Choice Awards, and more than 100 Golden and Platinum discs. In 2004, he was inducted into the Dance Music Hall of Fame.